Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.35 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30739304 | 0.86 | MAPT (0.45) | NPC1RAB9AMAPTLMNABCHE | |
| SCHEMBL27963663 | 0.86 | MAPT (0.45) | NPC1RAB9AMAPTLMNABCHE | |
| SCHEMBL9369351 | 0.77 | NPC1 (0.52) | NPC1RAB9AMAPTLMNABCHE | |
| SCHEMBL3307087 | 0.77 | NPC1 (0.52) | NPC1RAB9AMAPTLMNABCHE | |
| SCHEMBL29396289 | 0.77 | NPC1 (0.52) | NPC1RAB9AMAPTLMNABCHE | |
| SCHEMBL3275092 | 0.75 | PTGER3 (0.53) | MAPTLMNAPTGER4PTGER3PTGER2 | |
| SCHEMBL9789287 | 0.72 | MAPT (0.49) | NPC1RAB9AMAPTLMNABCHE | |
| SCHEMBL7559547 | 0.70 | RAB9A (0.59) | NPC1RAB9AMAPTLMNABCHE | |
| SCHEMBL3183044 | 0.70 | MAPT (0.55) | NPC1RAB9AMAPTLMNABCHE | |
| SCHEMBL3183029 | 0.70 | MAPT (0.55) | NPC1RAB9AMAPTLMNABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050019438-A1 | Hop extracts and use thereof in the production of a medicament having estrogenic properties | BOURGES-SEVENIER CEDRIC (FR) | 2005-01-27 | — | — | US | claimed |
| EP-1381379-A1 | HOP EXTRACTS AND USE THEREOF IN THE PRODUCTION OF A MEDICAMENT HAVING ESTROGENIC PROPERTIES | BERKEM (FR) | 2004-01-21 | — | — | EP | claimed |
| WO-2002085393-A1 | HOP EXTRACTS AND USE THEREOF IN THE PRODUCTION OF A MEDICAMENT HAVING ESTROGENIC PROPERTIES | BERKEM (FR) | 2002-10-31 | — | — | WO | claimed |
| US-20050019438-A1 | Hop extracts and use thereof in the production of a medicament having estrogenic properties | BOURGES-SEVENIER CEDRIC (FR) | 2005-01-27 | — | — | US | disclosed |
| EP-1381379-A1 | HOP EXTRACTS AND USE THEREOF IN THE PRODUCTION OF A MEDICAMENT HAVING ESTROGENIC PROPERTIES | BERKEM (FR) | 2004-01-21 | — | — | EP | disclosed |
| WO-2002085393-A1 | HOP EXTRACTS AND USE THEREOF IN THE PRODUCTION OF A MEDICAMENT HAVING ESTROGENIC PROPERTIES | BERKEM (FR) | 2002-10-31 | — | — | WO | disclosed |