Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 6/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29178833 | 1.00 | ERN1 (0.35) | ERN1CSF1RCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL29178786 | 0.91 | ERN1 (0.36) | ERN1CSF1RCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL30739338 | 0.91 | ERN1 (0.36) | ERN1CSF1RCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL30739298 | 0.85 | EGFR (0.38) | LMNAHTTMAPK1HPGD | |
| SCHEMBL29178921 | 0.85 | EGFR (0.38) | LMNAHTTMAPK1HPGD | |
| SCHEMBL29178855 | 0.84 | PTGER1 (0.34) | ERN1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL30739319 | 0.84 | PTGER1 (0.34) | ERN1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL30739285 | 0.83 | MRGPRX4 (0.33) | ERN1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL29178900 | 0.83 | MRGPRX4 (0.33) | ERN1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL30739337 | 0.81 | PDK1 (0.32) | ERN1CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466897-A | Highly selective FGFR2 inhibitors | 深圳福沃药业有限公司 | 2024-01-30 | — | — | CN | disclosed |