Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CTSV | O60911 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSH | P09668 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3073965 | 1.00 | DDB1 (0.36) | DDB1CRBNHSD11B1ACHEHTR1A | |
| SCHEMBL3073962 | 1.00 | DDB1 (0.36) | DDB1CRBNHSD11B1ACHEHTR1A | |
| SCHEMBL11131918 | 0.78 | SMN1; SMN2 (0.47) | DDB1CRBNSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL11131933 | 0.78 | SMN1; SMN2 (0.47) | DDB1CRBNSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL11131926 | 0.78 | SMN1; SMN2 (0.47) | DDB1CRBNSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL13403264 | 0.77 | SMN1; SMN2 (0.46) | DDB1CRBNSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL25971632 | 0.73 | SLC6A3 (0.37) | ALDH1A1 | |
| SCHEMBL25971633 | 0.73 | SLC6A3 (0.37) | ALDH1A1 | |
| SCHEMBL7860296 | 0.69 | POLB (0.40) | DDB1CRBNSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL27470927 | 0.67 | CHRNA7 (0.43) | ACHEALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790753-B2 | Derivatives of N-[phenyl(alkylpiperidine-2-yl)methyl]benzamide, preparation method thereof and application of same in therapeutics | SANOFI-AVENTIS (FR) | 2010-09-07 | — | — | US | disclosed |
| EP-1682503-B1 | DERIVATIVES OF N-[PHENYL(ALKYLPIPERIDINE-2-YL)METHYL]BENZAMIDE, PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2007-04-11 | — | — | EP | disclosed |
| US-20060223861-A1 | Derivatives of N-[phenyl(alkylpiperidine-2-yl)methyl]benzamide, preparation method thereof and application of same in therapeutics | SANOFI-AVENTIS (FR) | 2006-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223861-A1 | Derivatives of N-[phenyl(alkylpiperidine-2-yl)methyl]benzamide, preparation method thereof and application of same in therapeutics | SNCA, CHRNA5, GABRE | DDB1 3033/4885CRBN 1241/4885HSD11B1 4329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.