SCHEMBL30739719

SCHEMBL30739719

COc1ccccc1C(=O)Nc1ccc(F)cc1

nearest known ligand 0.71

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.71
RAB9A P51151 4/20 0.71
ALDH1A1 P00352 2/20 0.71
KCNK3 O14649 3/20 0.69
KCNK9 Q9NPC2 3/20 0.69
SMN1; SMN2 Q16637 4/20 0.68
TP53 P04637 2/20 0.68
NPC1 O15118 2/20 0.68
MAPK1 P28482 2/20 0.68
KMT2A Q03164 5/20 0.67
GAA P10253 1/20 0.66
LMNA P02545 2/20 0.66
MEN1 O00255 2/20 0.64
POLB P06746 2/20 0.64
KDM4E B2RXH2 1/20 0.63
AHR P35869 1/20 0.63
GFER P55789 1/20 0.63
RECQL P46063 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4429130 1.00 MAPT (0.71) MAPTRAB9AALDH1A1KCNK3KCNK9
SCHEMBL2721612 0.89 MAPT (0.73) MAPTRAB9AALDH1A1KCNK3KCNK9
SCHEMBL2362772 0.88 KMT2A (0.82) MAPTRAB9AALDH1A1KCNK3KCNK9
SCHEMBL5390989 0.87 MAPT (0.71) MAPTRAB9AALDH1A1KCNK3KCNK9
SCHEMBL3949532 0.87 KMT2A (0.78) MAPTRAB9AALDH1A1KCNK3KCNK9
SCHEMBL4429129 0.86 MAPT (0.69) MAPTRAB9AALDH1A1KCNK3KCNK9
SCHEMBL6294966 0.86 PNLIP (0.70) MAPTRAB9AALDH1A1KCNK3KCNK9
SCHEMBL678394 0.86 MAPT (0.69) MAPTRAB9AALDH1A1KCNK3KCNK9
SCHEMBL94630 0.86 MAPT (0.69) MAPTRAB9AALDH1A1KCNK3KCNK9
SCHEMBL4432153 0.86 MAPT (0.69) MAPTRAB9AALDH1A1KCNK3KCNK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118044519-A Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-05-17 CN disclosed
CN-110072842-B Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-02-02 CN disclosed