Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.71 |
| ▸ | JAK1 | P23458 | 2/20 | 0.71 |
| ▸ | TYK2 | P29597 | 2/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.61 |
| ▸ | MEN1 | O00255 | 8/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28326824 | 0.93 | KMT2A (0.73) | JAK2JAK1TYK2HTTNOD2 | |
| SCHEMBL16346420 | 0.88 | GAA (0.59) | JAK2JAK1TYK2HTTNOD2 | |
| SCHEMBL16583943 | 0.88 | GAA (0.59) | JAK2JAK1TYK2HTTNOD2 | |
| SCHEMBL30739821 | 0.86 | JAK2 (0.69) | JAK2JAK1TYK2HTTNOD2 | |
| SCHEMBL986128 | 0.86 | RAB9A (0.67) | JAK2JAK1TYK2HTTNOD2 | |
| SCHEMBL19576334 | 0.85 | GAA (0.56) | JAK2JAK1TYK2HTTNOD2 | |
| SCHEMBL10198748 | 0.85 | GAA (0.56) | JAK2JAK1TYK2HTTNOD2 | |
| SCHEMBL1057314 | 0.83 | JAK2 (0.65) | JAK2JAK1TYK2HTTNOD2 | |
| SCHEMBL678422 | 0.83 | JAK2 (0.65) | JAK2JAK1TYK2HTTNOD2 | |
| SCHEMBL7927691 | 0.83 | JAK2 (0.65) | JAK2JAK1TYK2HTTNOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118044519-A | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 科迪华农业科技有限责任公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-110072842-B | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 科迪华农业科技有限责任公司 | 2024-02-02 | — | — | CN | disclosed |