SCHEMBL30739818

SCHEMBL30739818

O=C(COC(F)(F)F)Nc1c(F)ccc(NC(=O)c2ccccc2Cl)c1F

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.49
HPGD P15428 2/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2C19 P33261 1/20 0.45
GRM4 Q14833 3/20 0.44
ALDH1A1 P00352 4/20 0.43
KMT2A Q03164 1/20 0.43
MAPT P10636 2/20 0.42
NPSR1 Q6W5P4 1/20 0.42
RAB9A P51151 2/20 0.42
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
TRPV1 Q8NER1 1/20 0.41
RORC P51449 1/20 0.40
NPC1 O15118 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
POLB P06746 1/20 0.39
KDR P35968 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30739985 0.84 HDAC1 (0.43) KDM4EALDH1A1KMT2ARAB9ANPC1
SCHEMBL29995165 0.83 KDM4E (0.49) KDM4EHPGDCYP1A2CYP2C19GRM4
SCHEMBL30739611 0.82 POLB (0.38) KDM4EALDH1A1KMT2AMAPTRAB9A
SCHEMBL30739588 0.81 F2R (0.57) KDM4EHPGDCYP1A2CYP2C19GRM4
SCHEMBL24281554 0.78 RAB9A (0.36) KDM4EGRM4ALDH1A1KMT2AMAPT
SCHEMBL24281919 0.78 RAB9A (0.36) KDM4EGRM4ALDH1A1KMT2AMAPT
SCHEMBL29493884 0.77 HPGD (0.51) KDM4EHPGDCYP1A2CYP2C19GRM4
SCHEMBL30739962 0.76 HDAC1 (0.41) KDM4EALDH1A1KMT2ARAB9ANPC1
SCHEMBL24282057 0.76 KMT2A (0.34) KDM4EGRM4ALDH1A1KMT2AMAPT
SCHEMBL24281837 0.76 MAPT (0.34) KDM4EHPGDALDH1A1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118044519-A Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-05-17 CN disclosed
CN-110072842-B Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-02-02 CN disclosed