Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TAS2R38 | P59533 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MDM4 | O15151 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3082651 | 0.95 | MAPT (0.54) | MAPTHDAC8ALDH1A1ALOX15TAS2R38 | |
| Benzenethiol SCHEMBL3078095 | 0.93 | MAPT (0.52) | MAPTHDAC8ALDH1A1ALOX15TAS2R38 | |
| SCHEMBL1158061 | 0.80 | ALDH1A1 (0.47) | MAPTHDAC8ALDH1A1ALOX15TAS2R38 | |
| SCHEMBL1694521 | 0.79 | MAPT (0.52) | MAPTHDAC8ALDH1A1ALOX15CA12 | |
| SCHEMBL3063686 | 0.78 | MAPT (0.52) | MAPTHDAC8ALDH1A1ALOX15CA12 | |
| SCHEMBL3077847 | 0.77 | MAPT (0.50) | MAPTHDAC8ALDH1A1ALOX15TAS2R38 | |
| SCHEMBL31175700 | 0.77 | MAPT (0.50) | MAPTHDAC8ALDH1A1TAS2R38CA12 | |
| SCHEMBL11767457 | 0.77 | MAPT (0.40) | MAPTHDAC8ALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL1696234 | 0.75 | MAPT (0.48) | MAPTHDAC8CA12CA1CA2 | |
| SCHEMBL18030779 | 0.74 | MAPT (0.58) | MAPTHDAC8ALDH1A1ALOX15CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534690-A1 | 2-SUBSTITUTED BICYCLIC BENZOHETEROCYCLIC COMPOUNDS AND THEIR USE AS SODIUM CHANNEL BLOCKERS | Euro-Celtique S.A. (LU) | 2005-06-01 | — | — | EP | claimed |
| US-20040152696-A1 | 2-substituted bicyclic benzoheterocyclic compounds and their use as sodium channel blockers | EURO-CELTIQUE S.A. | 2004-08-05 | — | — | US | claimed |
| WO-2004013111-A1 | 2-SUBSTITUTED BICYCLIC BENZOHETEROCYCLIC COMPOUNDS AND THEIR USE AS SODIUM CHANNEL BLOCKERS | EURO-CELTIQUE S.A. (LU) | 2004-02-12 | — | — | WO | claimed |
| CN-113285024-A | Semiconductor device having quantum dots, display device, imaging system, and moving object | 佳能株式会社 | 2021-08-20 | — | — | CN | disclosed |
| US-9457234-B2 | Golf ball | DUNLOP SPORTS CO. LTD. (JP) | 2016-10-04 | — | — | US | disclosed |
| US-9302158-B2 | Golf ball | DUNLOP SPORTS CO., LTD. (JP) | 2016-04-05 | — | — | US | disclosed |
| WO-2015053797-A2 | NOVEL SYNTHETIC ASPIRIN-MIMICS AND INNOVATIVE ANTIOXIDANTS AND THEIR USES | LU YANSONG (US) | 2015-04-16 | — | — | WO | disclosed |
| US-20140357406-A1 | GOLF BALL | DUNLOP SPORTS CO., LTD. (JP) | 2014-12-04 | — | — | US | disclosed |
| US-20140100058-A1 | GOLF BALL | Dunlop Sprorts Co., Ltd. (JP) | 2014-04-10 | — | — | US | disclosed |
| US-7833331-B2 | Non-toxic corrosion-protection pigments based on cobalt | UNIVERSITY OF DAYTON (US) | 2010-11-16 | — | — | US | disclosed |
| US-7789958-B2 | Non-toxic corrosion-protection pigments based on manganese | UNIVERSITY OF DAYTON (US) | 2010-09-07 | — | — | US | disclosed |
| US-20040016910-A1 | Non-toxic corrosion-protection rinses and seals based on rare earth elements | DAYTON, UNIVERSITY OF | 2004-01-29 | — | — | US | disclosed |
| US-20040011252-A1 | Non-toxic corrosion-protection pigments based on manganese | UNIVERSITY OF DAYTON | 2004-01-22 | — | — | US | disclosed |
| US-20030234063-A1 | Non-toxic corrosion-protection conversion coats based on cobalt | DAYTON, UNIVERSITY OF | 2003-12-25 | — | — | US | disclosed |
| US-20030230363-A1 | Non-toxic corrosion-protection rinses and seals based on cobalt | UNIVERSITY OF DAYTON | 2003-12-18 | — | — | US | disclosed |
| WO-2003060191-A2 | NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003060192-A1 | NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003060019-A1 | NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| US-5807813-A | Lubricating oil composition | IDEMITSU KOSAN CO., LTD. (JP) | 1998-09-15 | — | — | US | disclosed |
| EP-0783032-A1 | LUBRICATING OIL COMPOSITION | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1997-07-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152696-A1 | 2-substituted bicyclic benzoheterocyclic compounds and their use as sodium channel blockers | CACNA1C, CACNA1D, SCN2B | MAPT 1507/4885HDAC8 2110/4885ALDH1A1 803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.