Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.65 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.55 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL169319 | 1.00 | ESR2 (0.65) | ESR2NR1H2ABHD6TMEM97SIGMAR1 | |
| SCHEMBL2284685 | 0.96 | NR1H2 (0.61) | ESR2NR1H2ABHD6TMEM97SIGMAR1 | |
| SCHEMBL29883466 | 0.96 | NR1H2 (0.61) | ESR2NR1H2ABHD6TMEM97SIGMAR1 | |
| SCHEMBL1789713 | 0.93 | ESR2 (0.55) | ESR2NR1H2GPR119 | |
| SCHEMBL15878872 | 0.91 | ESR2 (0.51) | ESR2NR1H2ABHD6GPR119MAPK1 | |
| SCHEMBL29155326 | 0.85 | ESR2 (0.43) | ESR2TMEM97SIGMAR1ESR1 | |
| SCHEMBL3176570 | 0.84 | ABHD6 (0.47) | ESR2ABHD6TMEM97SIGMAR1ESR1 | |
| SCHEMBL14768550 | 0.83 | ESR2 (0.70) | ESR2NR1H2ABHD6TMEM97SIGMAR1 | |
| SCHEMBL29407529 | 0.83 | ESR2 (0.70) | ESR2NR1H2ABHD6TMEM97SIGMAR1 | |
| SCHEMBL168265 | 0.83 | ESR2 (0.70) | ESR2NR1H2ABHD6TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117412954-A | Synthesis of rapamycin analog compounds | 锐新医药公司 | 2024-01-16 | — | — | CN | disclosed |