Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 17/20 | 0.71 |
| ▸ | RAB9A | P51151 | 17/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.71 |
| ▸ | MEN1 | O00255 | 9/20 | 0.71 |
| ▸ | GAA | P10253 | 16/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | HPGD | P15428 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 16/20 | 0.61 |
| ▸ | MITF | O75030 | 4/20 | 0.61 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | XBP1 | P17861 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.60 |
| ▸ | RELA | Q04206 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26915307 | 1.00 | NPC1 (0.71) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL26935088 | 1.00 | NPC1 (0.71) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL12581545 | 0.89 | NPC1 (0.75) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL714967 | 0.87 | RAB9A (0.74) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL714966 | 0.87 | RAB9A (0.74) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL12581568 | 0.84 | NPC1 (0.61) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL2681914 | 0.81 | RAB9A (0.74) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL1164832 | 0.81 | GAA (0.72) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL1164830 | 0.81 | GAA (0.72) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL14348785 | 0.79 | RAB9A (0.62) | NPC1RAB9AKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117042759-A | IL-31 production inhibitor and pharmaceutical composition containing the same | 国立大学法人九州大学 | 2023-11-10 | — | — | CN | disclosed |