Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.47 |
| ▸ | SPR | P35270 | 1/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 5/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19549674 | 1.00 | GRAMD1A (0.47) | GRAMD1ASPRFGFR3KDRNPC1 | |
| SCHEMBL30145292 | 0.91 | HTR2C (0.41) | GRAMD1ASPRFGFR3KDRPDCD1 | |
| SCHEMBL20293398 | 0.91 | HTR2C (0.41) | GRAMD1ASPRFGFR3KDRPDCD1 | |
| SCHEMBL30504508 | 0.88 | GRAMD1A (0.47) | GRAMD1AFGFR3KDRNPC1RAB9A | |
| SCHEMBL30504550 | 0.88 | GRAMD1A (0.47) | GRAMD1AFGFR3KDRNPC1RAB9A | |
| SCHEMBL19549712 | 0.87 | PDCD1 (0.57) | GRAMD1AFGFR3KDRNPC1RAB9A | |
| SCHEMBL19549681 | 0.85 | GRAMD1A (0.47) | GRAMD1AFGFR3KDRNPC1RAB9A | |
| SCHEMBL19549770 | 0.84 | PDCD1 (0.54) | GRAMD1AFGFR3KDRNPC1RAB9A | |
| SCHEMBL6223701 | 0.84 | GRAMD1A (0.50) | GRAMD1AFGFR3KDRNPC1RAB9A | |
| SCHEMBL19549886 | 0.82 | GRAMD1A (0.42) | GRAMD1AFGFR3KDRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110582493-B | Benzoxazole derivatives as immunomodulators | 因赛特公司 | 2024-03-08 | — | — | CN | disclosed |