Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21225736 | 1.00 | SCN9A (0.41) | SCN9APPARGHTTPTGER3ALDH1A1 | |
| SCHEMBL21232718 | 0.89 | SCN9A (0.41) | SCN9AHTTPTGER3KDM4E | |
| SCHEMBL21225779 | 0.82 | PTGER4 (0.50) | — | |
| SCHEMBL21225778 | 0.82 | PTGER4 (0.50) | — | |
| SCHEMBL21225846 | 0.80 | PTGER4 (0.49) | PTGER3 | |
| SCHEMBL29225608 | 0.80 | SLC6A9 (0.44) | PTGER3 | |
| SCHEMBL21232942 | 0.78 | PDE2A (0.43) | PTGER3 | |
| SCHEMBL21232950 | 0.77 | KCNQ3 (0.42) | PPARGALDH1A1HPGD | |
| SCHEMBL21232949 | 0.77 | KCNQ3 (0.42) | PPARGALDH1A1HPGD | |
| SCHEMBL17908066 | 0.76 | ABCG2 (0.50) | HTTALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936138-B | Heterobicyclic compounds as EP4 receptor antagonists | 深圳市原力生命科学有限公司 | 2024-03-08 | — | — | CN | disclosed |