Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4956421 | 0.89 | KMT2A (0.59) | KMT2ALMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL10835203 | 0.88 | KMT2A (0.55) | KMT2ALMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL22453381 | 0.86 | KMT2A (0.54) | KMT2ALMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL22453460 | 0.85 | KMT2A (0.52) | KMT2AMEN1LMNATSHRALDH1A1 | |
| SCHEMBL4444645 | 0.85 | KMT2A (0.67) | KMT2ALMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL14691040 | 0.83 | KMT2A (0.50) | KMT2AMEN1LMNATSHRALDH1A1 | |
| SCHEMBL28281091 | 0.82 | AKR1C3 (0.50) | LMNATSHRALDH1A1TDP1KDM4E | |
| SCHEMBL28282462 | 0.81 | ALDH1A1 (0.44) | KMT2AMEN1LMNATSHRALDH1A1 | |
| SCHEMBL22452884 | 0.80 | KMT2A (0.48) | KMT2ALMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL10834309 | 0.78 | NOX1 (0.54) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |