Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | GLP1R | P43220 | 6/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29826142 | 1.00 | ACSS2 (0.46) | ACSS2KDM4EHTR7HTR6GLP1R | |
| SCHEMBL24900035 | 0.86 | ACSS2 (0.47) | ACSS2KDM4EHTR7HTR6GLP1R | |
| SCHEMBL30020641 | 0.86 | ACSS2 (0.47) | ACSS2KDM4EHTR7HTR6GLP1R | |
| SCHEMBL30740795 | 0.85 | ACSS2 (0.46) | ACSS2KDM4EHTR7HTR6GLP1R | |
| SCHEMBL29826815 | 0.85 | ACSS2 (0.46) | ACSS2KDM4EHTR7HTR6GLP1R | |
| SCHEMBL30740718 | 0.84 | ACSS2 (0.46) | ACSS2KDM4EHTR7HTR6GLP1R | |
| SCHEMBL24265338 | 0.84 | ACSS2 (0.46) | ACSS2KDM4EHTR7HTR6GLP1R | |
| SCHEMBL29559350 | 0.79 | BRD4 (0.47) | ACSS2KDM4EHTR7HTR6LCK | |
| SCHEMBL29825972 | 0.79 | GLP1R (0.51) | ACSS2KDM4EHTR7HTR6GLP1R | |
| SCHEMBL30740849 | 0.79 | GLP1R (0.51) | ACSS2KDM4EHTR7HTR6GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |