Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.62 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.45 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.45 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.45 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.45 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.45 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.45 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.45 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.45 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.45 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2775443 | 0.94 | GPR119 (0.66) | GPR119DGAT1LIPENPBWR1MCHR1 | |
| SCHEMBL28668694 | 0.87 | GPR119 (0.58) | GPR119LIPE | |
| SCHEMBL18089521 | 0.87 | GPR119 (0.58) | GPR119LIPE | |
| SCHEMBL6791900 | 0.85 | GPR119 (0.61) | GPR119LIPECACNB4CACNA1ACACNA1G | |
| SCHEMBL13060394 | 0.83 | GPR119 (0.63) | GPR119DGAT1NPBWR1MCHR1CACNB4 | |
| SCHEMBL14861989 | 0.82 | GPR119 (0.51) | GPR119DGAT1CACNB4CACNA1ACACNA1G | |
| SCHEMBL19147639 | 0.82 | GPR119 (0.62) | GPR119NPBWR1MCHR1CACNB4CACNA1A | |
| SCHEMBL941793 | 0.81 | GPR119 (0.64) | GPR119LIPENPBWR1MCHR1 | |
| SCHEMBL31748202 | 0.81 | GPR119 (0.67) | GPR119DGAT1NPBWR1MCHR1 | |
| SCHEMBL13993542 | 0.81 | GPR119 (0.67) | GPR119NPBWR1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |