Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | PTGFR | P43088 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | PTGIR | P43119 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30740817 | 0.81 | HDAC8 (0.52) | SMN1; SMN2ALDH1A1MRGPRX4LMNAMAPK1 | |
| SCHEMBL23631614 | 0.75 | MAPT (0.40) | HPGDKDM4ESMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6211536 | 0.74 | KDM4E (0.39) | KDM4EALDH1A1MAPTMAPK1TDP1 | |
| SCHEMBL6986597 | 0.73 | KDM4E (0.39) | HPGDKDM4ESMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6299234 | 0.73 | NQO2 (0.57) | HPGDKDM4ESMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL30740729 | 0.72 | SMN1; SMN2 (0.46) | HPGDKDM4ESMN1; SMN2ALDH1A1MRGPRX4 | |
| SCHEMBL5248861 | 0.71 | CHRM2 (0.38) | KDM4EALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL6986112 | 0.71 | LOXL2 (0.44) | HPGDKDM4ESMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL2097653 | 0.70 | IDO1 (0.65) | TBXA2RPTGFRPTGER3PTGER2PTGIR | |
| SCHEMBL18796637 | 0.69 | PDE3B (0.76) | HPGDKDM4ESMN1; SMN2ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |