Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22118870 | 0.84 | DAGLA (0.40) | DAGLANPSR1KDM4EALDH1A1CYP4A11 | |
| SCHEMBL9258762 | 0.83 | CYP1A2 (0.41) | KDM4EALDH1A1CYP4F2CYP4A11HTT | |
| SCHEMBL31434681 | 0.83 | DAGLA (0.39) | DAGLANPSR1KDM4EALDH1A1HTT | |
| SCHEMBL17130045 | 0.77 | ALDH1A1 (0.40) | DAGLANPSR1KDM4EALDH1A1KMT2A | |
| SCHEMBL163237 | 0.74 | NPSR1 (0.41) | DAGLANPSR1KDM4EALDH1A1CES1 | |
| SCHEMBL15540687 | 0.74 | NPSR1 (0.41) | DAGLANPSR1KDM4EALDH1A1MEN1 | |
| SCHEMBL21639139 | 0.73 | DAGLA (0.55) | DAGLANPSR1CES1MAPT | |
| SCHEMBL9980378 | 0.71 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL30153789 | 0.70 | NPSR1 (0.38) | DAGLANPSR1KDM4EALDH1A1MEN1 | |
| SCHEMBL5203591 | 0.69 | KDM4E (0.53) | NPSR1KDM4EALDH1A1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |