Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 4/20 | 0.56 |
| ▸ | EIF4E | P06730 | 5/20 | 0.50 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29158589 | 0.85 | EIF4E (0.45) | IKBKBEIF4EL3MBTL1POLBCYP1A2 | |
| SCHEMBL29158703 | 0.84 | EIF4E (0.43) | IKBKBEIF4ECDC7L3MBTL1POLB | |
| SCHEMBL21541929 | 0.84 | TARBP2 (0.48) | IKBKBEIF4EPOLBCYP1A2CYP2C19 | |
| SCHEMBL30740876 | 0.84 | TARBP2 (0.48) | IKBKBEIF4EPOLBCYP1A2CYP2C19 | |
| SCHEMBL27189100 | 0.84 | EIF4E (0.46) | IKBKBEIF4EL3MBTL1POLBKDM4E | |
| SCHEMBL30106366 | 0.83 | POLB (0.53) | IKBKBEIF4EPOLBALDH1A1LMNA | |
| SCHEMBL30106375 | 0.83 | EIF4E (0.45) | IKBKBEIF4EL3MBTL1POLBCYP1A2 | |
| SCHEMBL30741038 | 0.83 | EIF4E (0.48) | IKBKBEIF4ECDC7L3MBTL1CYP1A2 | |
| SCHEMBL27189055 | 0.83 | POLB (0.50) | EIF4EPOLBALDH1A1LMNAGSK3A | |
| SCHEMBL27189072 | 0.83 | EIF4E (0.45) | IKBKBEIF4EL3MBTL1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | disclosed |