Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | FOS | P01100 | 1/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 2/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30741023 | 0.89 | KDM4E (0.45) | MAPTKDM4EMAOBALDH1A1TP53 | |
| SCHEMBL30741035 | 0.89 | GCGR (0.49) | MAPTKDM4EMEN1KMT2AHSP90AA1 | |
| SCHEMBL30741092 | 0.88 | JAK2 (0.48) | MAPTKDM4EMEN1KMT2AHSP90AA1 | |
| SCHEMBL30741107 | 0.87 | JAK2 (0.48) | MAPTKDM4EMEN1KMT2AHSP90AA1 | |
| SCHEMBL30741004 | 0.86 | KDM4E (0.41) | MAPTKDM4EMEN1KMT2AHSP90AA1 | |
| SCHEMBL30741037 | 0.86 | KDM4E (0.43) | MAPTKDM4EMEN1KMT2AHSP90AA1 | |
| SCHEMBL30741066 | 0.84 | KDM4E (0.41) | MAPTKDM4EMEN1KMT2AHSP90AA1 | |
| SCHEMBL30741020 | 0.84 | AR (0.51) | MAPTKDM4EL3MBTL1ALDH1A1RAB9A | |
| SCHEMBL30740997 | 0.83 | KDM4E (0.48) | MAPTKDM4EMEN1KMT2AHSP90AA1 | |
| SCHEMBL30741086 | 0.83 | KDM4E (0.43) | MAPTKDM4EMEN1KMT2AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | disclosed |