Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 2/20 | 0.43 |
| ▸ | JAK3 | P52333 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30740966 | 0.91 | SMN1; SMN2 (0.48) | KDM4EALDH1A1GAAHPGDMAPT | |
| SCHEMBL30741023 | 0.91 | KDM4E (0.45) | KDM4EALDH1A1GAAHPGDMAPT | |
| SCHEMBL30741053 | 0.90 | JAK2 (0.47) | KDM4EALDH1A1GAAHPGDMAPT | |
| SCHEMBL30741000 | 0.90 | JAK2 (0.47) | KDM4EALDH1A1GAAHPGDMAPT | |
| SCHEMBL30741058 | 0.89 | KDM4E (0.45) | KDM4EALDH1A1GAAHPGDMAPT | |
| SCHEMBL30741106 | 0.88 | NR1H2 (0.49) | KDM4EALDH1A1GAAHPGDMAPT | |
| SCHEMBL30741087 | 0.88 | CNR2 (0.48) | KDM4EALDH1A1GAAHPGDMAPT | |
| SCHEMBL30741018 | 0.87 | KDM4E (0.42) | KDM4EALDH1A1GAAHPGDMAPT | |
| SCHEMBL30741115 | 0.87 | MAPT (0.50) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL30741035 | 0.85 | GCGR (0.49) | KDM4EMAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | disclosed |