Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | JAK2 | O60674 | 7/20 | 0.44 |
| ▸ | JAK3 | P52333 | 7/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30740997 | 0.91 | KDM4E (0.48) | SMN1; SMN2KDM4EJAK2JAK3MRGPRX4 | |
| SCHEMBL30741092 | 0.88 | JAK2 (0.48) | SMN1; SMN2KDM4EJAK2JAK3MAPT | |
| SCHEMBL30741023 | 0.88 | KDM4E (0.45) | KDM4EJAK2JAK3MRGPRX4MAPT | |
| SCHEMBL30741053 | 0.87 | JAK2 (0.47) | SMN1; SMN2KDM4EJAK2JAK3CSNK1D | |
| SCHEMBL30741000 | 0.87 | JAK2 (0.47) | SMN1; SMN2KDM4EJAK2JAK3MRGPRX4 | |
| SCHEMBL30741058 | 0.86 | KDM4E (0.45) | SMN1; SMN2KDM4EJAK2JAK3MRGPRX4 | |
| SCHEMBL30741106 | 0.85 | NR1H2 (0.49) | KDM4EJAK2JAK3MRGPRX4MAPT | |
| SCHEMBL30741087 | 0.85 | CNR2 (0.48) | SMN1; SMN2KDM4EJAK2JAK3MRGPRX4 | |
| SCHEMBL30741115 | 0.84 | MAPT (0.50) | KDM4EMAPTALDH1A1RAB9AMEN1 | |
| SCHEMBL30741018 | 0.84 | KDM4E (0.42) | KDM4EJAK2JAK3MRGPRX4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | disclosed |