SCHEMBL30741015

SCHEMBL30741015

CCOC(=O)c1cc(-c2ccc(OC)cc2)[nH]c1-c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GCGR P47871 2/20 0.60
PDE3B Q13370 2/20 0.55
PDE3A Q14432 2/20 0.55
CDC7 O00311 1/20 0.54
ALDH1A1 P00352 4/20 0.49
CYP2C9 P11712 2/20 0.49
CYP2C19 P33261 2/20 0.49
CYP1A2 P05177 1/20 0.49
GAA P10253 1/20 0.49
HPGD P15428 1/20 0.49
LMNA P02545 1/20 0.49
HTT P42858 1/20 0.48
MAPK10 P53779 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
MAPT P10636 2/20 0.47
TP53 P04637 1/20 0.47
POLB P06746 1/20 0.47
MDM2 Q00987 1/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30741032 0.89 ALDH1A1 (0.56) GCGRPDE3BPDE3ACDC7ALDH1A1
SCHEMBL4184868 0.88 GCGR (0.77) GCGRCDC7HTTMAPK10SMN1; SMN2
SCHEMBL29159037 0.85 GCGR (0.57) GCGRPDE3BPDE3AALDH1A1CYP1A2
SCHEMBL29551776 0.85 GCGR (0.49) GCGRCDC7ALDH1A1GAAHPGD
SCHEMBL30741046 0.85 GCGR (0.54) GCGRCDC7GAALMNAHTT
SCHEMBL30741082 0.84 GCGR (0.58) GCGRPDE3BPDE3ACDC7ALDH1A1
SCHEMBL30740926 0.84 GCGR (0.58) GCGRPDE3BPDE3ACDC7ALDH1A1
SCHEMBL30741084 0.84 GCGR (0.58) GCGRPDE3BPDE3ACDC7ALDH1A1
SCHEMBL4183471 0.84 GCGR (0.78) GCGRPDE3BPDE3ACDC7
SCHEMBL30741085 0.83 GCGR (0.57) GCGRPDE3BPDE3ACDC7ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117396465-A Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same 阿斯克里斯有限公司 2024-01-12 CN disclosed