Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | NNMT | P40261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | ADA | P00813 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20722463 | 0.88 | KMT2A (0.37) | KMT2APIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL21704264 | 0.86 | KCNJ1 (0.34) | KMT2APIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL20722848 | 0.82 | PTGER4 (0.39) | LCKKDM4ETUBB4ATUBBTUBA3C | |
| SCHEMBL20731185 | 0.76 | PIK3CB (0.35) | KMT2APIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL30741055 | 0.75 | HPGDS (0.43) | KMT2ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL21704217 | 0.74 | MAPT (0.34) | KMT2AKDM4ELMNA | |
| SCHEMBL23938065 | 0.72 | KDM4E (0.33) | KMT2AKDM4E | |
| SCHEMBL20722578 | 0.72 | HTR2A (0.34) | KMT2AGRM2KDM4E | |
| SCHEMBL14822494 | 0.67 | MGAM (0.44) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL30479467 | 0.67 | MGAM (0.44) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112823037-B | Inhibition of deubiquitinase USP25 and USP28 | 瓦洛健康股份有限公司 | 2023-12-19 | — | — | CN | disclosed |