Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 6/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8957480 | 0.88 | GPR84 (0.48) | CFTRGPR84CYP2A6CSNK2A1MEN1 | |
| SCHEMBL8957501 | 0.80 | GPR84 (0.46) | CFTRGPR84CYP2A6CSNK2A1MEN1 | |
| SCHEMBL14616743 | 0.79 | GPR84 (0.44) | CFTRGPR84CYP2A6CSNK2A1MEN1 | |
| SCHEMBL13285075 | 0.79 | GPR84 (0.44) | CFTRGPR84CYP2A6CSNK2A1MEN1 | |
| SCHEMBL8957473 | 0.79 | GPR84 (0.40) | CFTRGPR84CYP2A6CSNK2A1MEN1 | |
| SCHEMBL9004444 | 0.79 | CFTR (0.40) | CFTRGPR84CYP2A6CSNK2A1MEN1 | |
| SCHEMBL396029 | 0.78 | GPR84 (0.42) | CFTRGPR84CYP2A6CSNK2A1MEN1 | |
| SCHEMBL8957446 | 0.78 | GPR84 (0.62) | CFTRGPR84CYP2A6CSNK2A1MEN1 | |
| SCHEMBL8529327 | 0.78 | CSNK2A1 (0.55) | CFTRGPR84CYP2A6CSNK2A1MEN1 | |
| SCHEMBL8957459 | 0.78 | CSNK2A1 (0.50) | CFTRGPR84CYP2A6CSNK2A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113683554-B | Pyrrolopiperidone condensed ring derivative and synthetic method and application thereof | 重庆文理学院 | 2024-01-16 | — | — | CN | disclosed |