Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 2/20 | 0.58 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 6/20 | 0.53 |
| ▸ | CA1 | P00915 | 6/20 | 0.53 |
| ▸ | CA2 | P00918 | 6/20 | 0.53 |
| ▸ | CA9 | Q16790 | 6/20 | 0.53 |
| ▸ | CDK8 | P49336 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21295340 | 1.00 | RAF1 (0.58) | RAF1CXCR2MEN1LMNAMAPT | |
| SCHEMBL30744018 | 0.93 | RAF1 (0.62) | RAF1CXCR2MEN1LMNAMAPT | |
| SCHEMBL21295406 | 0.93 | RAF1 (0.62) | RAF1CXCR2MEN1LMNAMAPT | |
| SCHEMBL12994776 | 0.87 | HPGD (0.65) | MEN1LMNAMAPTKMT2ANPSR1 | |
| SCHEMBL6568524 | 0.84 | CXCR2 (0.77) | CXCR2MEN1LMNAMAPTKMT2A | |
| SCHEMBL21295538 | 0.83 | RAF1 (0.58) | RAF1MEN1LMNAMAPTKMT2A | |
| SCHEMBL22829287 | 0.82 | PGR (0.59) | MAPTRAB9ASMN1; SMN2NPC1MAPK14 | |
| SCHEMBL13224739 | 0.81 | MAPK1 (0.59) | CXCR2MEN1LMNAMAPTKMT2A | |
| SCHEMBL14384849 | 0.80 | RAF1 (0.56) | RAF1MEN1MAPTKMT2ARAB9A | |
| SCHEMBL5853268 | 0.80 | CXCR2 (0.74) | CXCR2MEN1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111819172-B | Triazine derivatives for the treatment of neurotrophin related diseases | 阿泽克制药公司 | 2024-02-06 | — | — | CN | disclosed |