Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 4/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21295384 | 1.00 | SLC6A4 (0.49) | SLC6A4HTR6PDE4AHTR1ASLC6A2 | |
| SCHEMBL21295363 | 0.82 | NTRK1 (0.58) | SLC6A4HTR6PDE4AHTR1ASLC6A2 | |
| SCHEMBL30743989 | 0.82 | NTRK1 (0.58) | SLC6A4HTR6PDE4AHTR1ASLC6A2 | |
| SCHEMBL19990170 | 0.78 | MAOA (0.56) | MAOBMAOANCOA1NCOA3CYP1A2 | |
| SCHEMBL987135 | 0.78 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20021949 | 0.77 | HRH1 (0.50) | PDE4ANCOA1NCOA3HRH1PDE4B | |
| SCHEMBL5704547 | 0.76 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17865580 | 0.76 | MEN1 (0.59) | SLC6A4SLC6A2SLC6A3MAOBMAOA | |
| SCHEMBL21295533 | 0.76 | CYP19A1 (0.53) | SLC6A4HTR6SLC6A2SLC6A3CYP1A2 | |
| SCHEMBL21305416 | 0.76 | PDE4D (0.52) | SLC6A4HTR6PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111819172-B | Triazine derivatives for the treatment of neurotrophin related diseases | 阿泽克制药公司 | 2024-02-06 | — | — | CN | disclosed |