Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.56 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.56 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MLNR | O43193 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21295551 | 1.00 | NTRK1 (0.56) | NTRK1NTRK3NTRK2MEN1KMT2A | |
| SCHEMBL21295533 | 0.84 | CYP19A1 (0.53) | MEN1KMT2AMAPTSLC6A4CYP19A1 | |
| SCHEMBL1157591 | 0.83 | PDE4D (0.55) | KMT2ALMNASMN1; SMN2PDE4DPDE4A | |
| SCHEMBL1157300 | 0.81 | PDE4D (0.57) | MEN1KMT2AMAPTCYP19A1LMNA | |
| SCHEMBL29125419 | 0.81 | PDE4D (0.55) | MEN1KMT2ALMNACYP3A4CYP2C9 | |
| SCHEMBL29125417 | 0.81 | PDE4D (0.55) | MEN1KMT2ALMNACYP3A4CYP2C9 | |
| SCHEMBL16385491 | 0.79 | TDP1 (0.51) | MEN1KMT2AMAPTCYP19A1CYP1A2 | |
| SCHEMBL21295348 | 0.79 | CYP19A1 (0.42) | MEN1KMT2AMAPTCYP19A1CYP1A2 | |
| SCHEMBL21295363 | 0.79 | NTRK1 (0.58) | NTRK1NTRK3NTRK2SLC6A4SLC6A2 | |
| SCHEMBL31481195 | 0.79 | HSPB1 (0.45) | MEN1KMT2AMAPTCYP19A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111819172-B | Triazine derivatives for the treatment of neurotrophin related diseases | 阿泽克制药公司 | 2024-02-06 | — | — | CN | disclosed |