Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.62 |
| ▸ | MAPT | P10636 | 11/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21295361 | 1.00 | MEN1 (0.62) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL30744032 | 0.88 | MAPT (0.52) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL21295540 | 0.88 | MAPT (0.52) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL21295391 | 0.82 | MEN1 (0.63) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL30744020 | 0.82 | MEN1 (0.63) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL4555017 | 0.81 | MAPT (0.71) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL21295336 | 0.80 | MAPT (0.62) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL30743994 | 0.80 | MAPT (0.62) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL8703652 | 0.80 | KMT2A (0.66) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL21295431 | 0.80 | STK39 (0.58) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111819172-B | Triazine derivatives for the treatment of neurotrophin related diseases | 阿泽克制药公司 | 2024-02-06 | — | — | CN | disclosed |