Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.54 |
| ▸ | TERT | O14746 | 6/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.50 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21801111 | 1.00 | CYP1B1 (0.54) | CYP1B1TERTCYP1A1CYP1A2MCL1 | |
| SCHEMBL10215550 | 0.87 | TERT (0.56) | CYP1B1TERTCYP1A1CYP1A2MCL1 | |
| Hydrochloric Acid SCHEMBL312701 | 0.86 | TERT (0.55) | CYP1B1TERTCYP1A1CYP1A2MCL1 | |
| SCHEMBL30744102 | 0.85 | CSNK2A2 (0.59) | CYP1B1TERTCYP1A1CYP1A2MCL1 | |
| SCHEMBL21801212 | 0.85 | CSNK2A2 (0.53) | TERTMCL1BRD4KDM4EALDH1A1 | |
| SCHEMBL30744106 | 0.85 | CSNK2A2 (0.53) | TERTMCL1BRD4KDM4EALDH1A1 | |
| SCHEMBL21801209 | 0.85 | CSNK2A2 (0.59) | CYP1B1TERTCYP1A1CYP1A2MCL1 | |
| SCHEMBL21801304 | 0.82 | TERT (0.51) | CYP1B1TERTCYP1A1MCL1BRD4 | |
| SCHEMBL30744114 | 0.82 | TERT (0.51) | CYP1B1TERTCYP1A1MCL1BRD4 | |
| SCHEMBL21801095 | 0.82 | TDP1 (0.64) | CYP1B1TERTCYP1A1CYP1A2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601743-B | Flavone compounds for the treatment and prevention of hepatitis b virus diseases | 豪夫迈·罗氏有限公司 | 2023-12-19 | — | — | CN | disclosed |