Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 7/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.48 |
| ▸ | LOX | P28300 | 4/20 | 0.46 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | ELOVL1 | Q9BW60 | 2/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21492519 | 1.00 | LOXL2 (0.51) | LOXL2HRH4CXCR4LOXLOXL3 | |
| SCHEMBL31421129 | 0.98 | LOXL2 (0.53) | LOXL2HRH4CXCR4LOXLOXL3 | |
| SCHEMBL4098507 | 0.98 | LOXL2 (0.53) | LOXL2HRH4CXCR4LOXLOXL3 | |
| SCHEMBL17379520 | 0.95 | LOXL2 (0.53) | LOXL2HRH4CXCR4LOXLOXL3 | |
| SCHEMBL31421498 | 0.95 | LOXL2 (0.53) | LOXL2HRH4CXCR4LOXLOXL3 | |
| SCHEMBL29793576 | 0.87 | CXCR4 (0.49) | LOXL2HRH4CXCR4KLKB1KLK1 | |
| SCHEMBL2459118 | 0.83 | PIK3CA (0.54) | LOXL2LOXLOXL3SMN1; SMN2OPRM1 | |
| SCHEMBL18888320 | 0.83 | HRH4 (0.54) | HRH4CXCR4NPC1TSHRRECQL | |
| SCHEMBL3752158 | 0.83 | HRH4 (0.50) | HRH4CXCR4KLKB1KLK1NPC1 | |
| SCHEMBL15504891 | 0.83 | HRH4 (0.50) | HRH4CXCR4KLKB1KLK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119486725-A | (2E) Mixtures and uses of (E) -3- (1, 3-benzodioxol-5-yl) -N-phenyl-N- (tetrahydro-3-furanyl) -2-propenamide | 西姆莱斯有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-112218865-B | Pteridinone compounds and uses thereof | 沃泰克斯药物股份有限公司 | 2024-03-12 | — | — | CN | disclosed |