Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.38 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28532083 | 1.00 | SCD (0.42) | SCDHDAC3HDAC8NCOR2L3MBTL1 | |
| SCHEMBL30060309 | 0.85 | HDAC3 (0.46) | SCDHDAC3HDAC8NCOR2L3MBTL1 | |
| SCHEMBL21492752 | 0.85 | KLKB1 (0.44) | SCDKLKB1GAASCD5 | |
| SCHEMBL24400371 | 0.82 | HDAC3 (0.42) | SCDHDAC3HDAC8NCOR2L3MBTL1 | |
| SCHEMBL30744352 | 0.82 | HDAC3 (0.42) | SCDHDAC3HDAC8NCOR2L3MBTL1 | |
| SCHEMBL24973943 | 0.80 | SCD (0.58) | SCDHDAC3HDAC8NCOR2L3MBTL1 | |
| SCHEMBL21432150 | 0.80 | GAA (0.55) | SCDHDAC3HDAC8NCOR2L3MBTL1 | |
| SCHEMBL29376075 | 0.77 | KDM4E (0.42) | SCDHDAC3HDAC8NCOR2L3MBTL1 | |
| SCHEMBL28518798 | 0.75 | SCD (0.43) | SCDHDAC3HDAC8NCOR2L3MBTL1 | |
| SCHEMBL21491992 | 0.75 | KLKB1 (0.41) | SCDKLKB1SCD5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218865-B | Pteridinone compounds and uses thereof | 沃泰克斯药物股份有限公司 | 2024-03-12 | — | — | CN | disclosed |