Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.38 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24400371 | 1.00 | HDAC3 (0.42) | HDAC3HDAC8NCOR2L3MBTL1RORC | |
| SCHEMBL21491800 | 0.90 | KLKB1 (0.42) | RORCKLKB1PPARDGLSNAMPT | |
| SCHEMBL28529563 | 0.88 | KLKB1 (0.39) | RORCKLKB1PPARDGLSNAMPT | |
| SCHEMBL30060309 | 0.86 | HDAC3 (0.46) | HDAC3HDAC8NCOR2L3MBTL1SCD | |
| SCHEMBL10263975 | 0.85 | L3MBTL1 (0.50) | L3MBTL1GLSNAMPTCA1CA2 | |
| SCHEMBL21491889 | 0.85 | KLKB1 (0.44) | KLKB1PPARDGLSNAMPT | |
| SCHEMBL21503621 | 0.83 | CA1 (0.42) | L3MBTL1PPARDGLSNAMPTCA12 | |
| SCHEMBL30057190 | 0.83 | CA1 (0.42) | L3MBTL1PPARDGLSNAMPTCA12 | |
| SCHEMBL30744381 | 0.82 | SCD (0.42) | HDAC3HDAC8NCOR2L3MBTL1SCD | |
| SCHEMBL28532083 | 0.82 | SCD (0.42) | HDAC3HDAC8NCOR2L3MBTL1SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218865-B | Pteridinone compounds and uses thereof | 沃泰克斯药物股份有限公司 | 2024-03-12 | — | — | CN | disclosed |