Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24938934 | 1.00 | HPGD (0.42) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9942499 | 0.94 | USP2 (0.44) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL733741 | 0.94 | USP2 (0.44) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL734925 | 0.94 | USP2 (0.44) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL18204175 | 0.87 | NR1H2 (0.40) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL27144761 | 0.85 | HPGD (0.49) | HPGDMAPTUSP2SMN1; SMN2EPHX1 | |
| SCHEMBL16112353 | 0.84 | HPGD (0.41) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL17107678 | 0.83 | NR1H2 (0.41) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL30186133 | 0.83 | USP2 (0.45) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL2904469 | 0.83 | USP2 (0.45) | HPGDMEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117062811-A | 3- (1-oxo-isoindolin-2-yl) piperidine-2, 6-dione derivatives and medical use thereof | 诺华股份有限公司 | 2023-11-14 | — | — | CN | disclosed |