Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21200017 | 0.79 | KDM4E (0.46) | TSHRTDP1L3MBTL1GAAALDH1A1 | |
| SCHEMBL21199946 | 0.79 | HPGD (0.39) | TSHRGAAALDH1A1KDM4EHPGD | |
| SCHEMBL21200395 | 0.79 | POLB (0.42) | TSHRGAAALDH1A1KDM4EHPGD | |
| SCHEMBL29866777 | 0.79 | KDM4E (0.46) | TSHRTDP1L3MBTL1GAAALDH1A1 | |
| SCHEMBL20944473 | 0.78 | HCRTR1 (0.44) | CYP11B2GAAALDH1A1KDM4EHPGD | |
| SCHEMBL6103259 | 0.78 | NQO2 (0.45) | TSHRTDP1L3MBTL1GAAALDH1A1 | |
| SCHEMBL31705111 | 0.78 | SLC6A3 (0.41) | TSHRGAAALDH1A1KDM4EHPGD | |
| SCHEMBL21199816 | 0.78 | SLC6A3 (0.41) | TSHRGAAALDH1A1KDM4EHPGD | |
| SCHEMBL12615803 | 0.78 | POLB (0.41) | TSHRGAAALDH1A1KDM4EHPGD | |
| SCHEMBL2711058 | 0.77 | TSHR (0.42) | TSHRL3MBTL1GAAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |