Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29278618 | 1.00 | NOTUM (0.59) | NOTUMKDM4EPOLBCFTRGAA | |
| SCHEMBL20963785 | 1.00 | NOTUM (0.59) | NOTUMKDM4EPOLBCFTRGAA | |
| SCHEMBL475762 | 0.85 | NOTUM (0.77) | NOTUMKDM4EPOLBCFTRGAA | |
| SCHEMBL30614560 | 0.83 | KDM4E (0.46) | NOTUMKDM4EPOLBGAACA12 | |
| SCHEMBL1999038 | 0.82 | NOTUM (0.77) | NOTUMKDM4EPOLBCFTRGAA | |
| SCHEMBL25301773 | 0.81 | KDM4E (0.47) | KDM4EPOLBGAACA12CA1 | |
| SCHEMBL30497213 | 0.81 | KDM4E (0.47) | KDM4EPOLBGAACA12CA1 | |
| SCHEMBL20944376 | 0.81 | CES2 (0.46) | KDM4EPOLBGAACES2LMNA | |
| SCHEMBL20944373 | 0.81 | CES2 (0.46) | KDM4EPOLBGAACES2LMNA | |
| SCHEMBL627579 | 0.80 | CES2 (0.50) | POLBGAACES2LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |