Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MELK | Q14680 | 2/20 | 0.52 |
| ▸ | PNMT | P11086 | 4/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308122 | 1.00 | MELK (0.52) | MELKPNMTSLC2A1ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL29903254 | 0.98 | MELK (0.51) | MELKPNMTSLC2A1ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL1017102 | 0.98 | MELK (0.51) | MELKPNMTSLC2A1ADRA2AADRA2B | |
| SCHEMBL1035136 | 0.94 | ASIC3 (0.47) | MELK | |
| SCHEMBL29784680 | 0.94 | ASIC3 (0.47) | MELK | |
| Hydrochloric Acid SCHEMBL1264208 | 0.92 | F2 (0.46) | MELKSLC2A1 | |
| SCHEMBL12486922 | 0.91 | MELK (0.44) | MELK | |
| SCHEMBL1263166 | 0.90 | MELK (0.50) | MELKSLC2A1 | |
| SCHEMBL30043640 | 0.87 | CA1 (0.50) | — | |
| SCHEMBL330093 | 0.87 | CA1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |