Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 14/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745156 | 0.89 | MET (0.72) | MET | |
| SCHEMBL29151086 | 0.89 | MET (0.72) | MET | |
| SCHEMBL3841596 | 0.84 | MET (0.67) | METPOLBMEN1KMT2APDE4A | |
| SCHEMBL3843640 | 0.83 | MET (0.79) | METPOLBMEN1KMT2ATP53 | |
| SCHEMBL29151080 | 0.80 | MET (0.65) | METPOLBMEN1KMT2A | |
| SCHEMBL30745140 | 0.80 | MET (0.65) | METPOLBMEN1KMT2A | |
| SCHEMBL11140135 | 0.75 | POLB (0.74) | POLBMEN1KMT2ATP53PDE4A | |
| SCHEMBL23297311 | 0.74 | MEN1 (0.66) | POLBMEN1KMT2ATP53PDE4A | |
| SCHEMBL3862486 | 0.74 | MET (0.69) | MET | |
| SCHEMBL2465372 | 0.73 | MET (0.65) | METMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510470-A | Pyridazinone compounds and application thereof | 暨南大学 | 2024-02-06 | — | — | CN | disclosed |