Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 5/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29151033 | 1.00 | PDGFRB (0.34) | PDGFRBPDGFRAMETDYRK1ANPC1 | |
| SCHEMBL29151025 | 0.85 | KDM4E (0.39) | PDGFRBPDGFRAMETDYRK1ANPC1 | |
| SCHEMBL30745169 | 0.85 | KDM4E (0.39) | PDGFRBPDGFRAMETDYRK1ANPC1 | |
| SCHEMBL14756190 | 0.85 | TAAR1 (0.46) | TDP1ALDH1A1MAPTCYP1A2CYP2D6 | |
| SCHEMBL14756200 | 0.81 | TAAR1 (0.50) | NPSR1POLBHPGDALDH1A1MAPT | |
| SCHEMBL17242123 | 0.81 | MALT1 (0.34) | PDGFRBPDGFRAMETDYRK1ANPC1 | |
| SCHEMBL6519685 | 0.81 | ROCK1 (0.41) | DYRK1ANPC1HTTBACE1 | |
| SCHEMBL31717019 | 0.81 | DYRK1A (0.34) | PDGFRBPDGFRAMETDYRK1ANPC1 | |
| SCHEMBL2147979 | 0.81 | HSD17B10 (0.37) | METDYRK1ANPC1BIRC5 | |
| SCHEMBL18563403 | 0.81 | CYP1A2 (0.41) | PDGFRBPDGFRANPC1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510470-A | Pyridazinone compounds and application thereof | 暨南大学 | 2024-02-06 | — | — | CN | disclosed |