Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 2/20 | 0.33 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29151025 | 1.00 | KDM4E (0.39) | KDM4EALDH1A1ALOX5GAAMAPT | |
| SCHEMBL2147979 | 0.86 | HSD17B10 (0.37) | CA2CDK8MAP4K4METNPC1 | |
| SCHEMBL30745166 | 0.85 | PDGFRB (0.34) | ALDH1A1MAPTBACE1METPDGFRB | |
| SCHEMBL29151033 | 0.85 | PDGFRB (0.34) | ALDH1A1MAPTBACE1METPDGFRB | |
| SCHEMBL14756190 | 0.83 | TAAR1 (0.46) | KDM4EALDH1A1GAAMAPTBACE1 | |
| SCHEMBL11154924 | 0.80 | CYP1A2 (0.49) | KDM4EALDH1A1ALOX5GAAMAPT | |
| SCHEMBL14756200 | 0.80 | TAAR1 (0.50) | KDM4EALDH1A1MAPT | |
| SCHEMBL31717019 | 0.79 | DYRK1A (0.34) | ALDH1A1MAPTBACE1METPDGFRB | |
| SCHEMBL17242123 | 0.79 | MALT1 (0.34) | ALDH1A1MAPTBACE1METPDGFRB | |
| SCHEMBL6519685 | 0.79 | ROCK1 (0.41) | BACE1CA2NPC1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510470-A | Pyridazinone compounds and application thereof | 暨南大学 | 2024-02-06 | — | — | CN | disclosed |