Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PDE4A | P27815 | 3/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29151105 | 1.00 | LMNA (0.56) | LMNAMEN1KMT2APDE4APDE4B | |
| SCHEMBL11743874 | 0.85 | SMN1; SMN2 (0.55) | LMNAMEN1KMT2APDE4APDE4B | |
| SCHEMBL12595734 | 0.85 | LMNA (0.60) | LMNAMEN1KMT2APDE4APDE4B | |
| SCHEMBL8305159 | 0.85 | LMNA (0.51) | LMNAMEN1KMT2APDE4APDE4B | |
| SCHEMBL31703201 | 0.85 | LMNA (0.51) | LMNAMEN1KMT2APDE4APDE4B | |
| SCHEMBL11733995 | 0.85 | LMNA (0.51) | LMNAMEN1KMT2APDE4APDE4B | |
| SCHEMBL1951453 | 0.84 | CYP1A2 (0.56) | LMNAMEN1KMT2APDE4APDE4B | |
| SCHEMBL1769907 | 0.82 | KDR (0.50) | LMNAMEN1KMT2APDE4APDE4B | |
| SCHEMBL27624079 | 0.81 | PDE4A (0.48) | LMNAMEN1KMT2APDE4APDE4B | |
| SCHEMBL3452908 | 0.80 | LMNA (0.80) | LMNAMEN1KMT2APDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510470-A | Pyridazinone compounds and application thereof | 暨南大学 | 2024-02-06 | — | — | CN | disclosed |