Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 2/20 | 0.85 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TACR1 | P25103 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ACP1 | P24666 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.46 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.46 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20418419 | 1.00 | ULK1 (0.85) | ULK1MAPTMEN1KMT2ATACR1 | |
| SCHEMBL29520034 | 1.00 | ULK1 (0.85) | ULK1MAPTMEN1KMT2ATACR1 | |
| SCHEMBL31252452 | 0.80 | ULK1 (0.56) | ULK1MAPTKMT2ATACR1SMN1; SMN2 | |
| SCHEMBL6719158 | 0.76 | ULK1 (0.61) | ULK1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31252380 | 0.74 | POLB (0.49) | ULK1KMT2ASMN1; SMN2HTTNPC1 | |
| SCHEMBL31252496 | 0.74 | POLB (0.49) | ULK1KMT2ASMN1; SMN2HTTNPC1 | |
| SCHEMBL20418676 | 0.73 | ULK1 (0.56) | ULK1MAPTKMT2ASMN1; SMN2HTT | |
| SCHEMBL20418423 | 0.73 | ULK1 (0.56) | ULK1MAPTKMT2ASMN1; SMN2HTT | |
| SCHEMBL6718043 | 0.72 | ULK1 (0.56) | ULK1MAPTMEN1KMT2AHTT | |
| SCHEMBL6715842 | 0.72 | ULK1 (0.55) | ULK1MAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240000753-A1 | METHODS AND COMPOSITIONS TO INCREASE LIFESPAN AND HEALTHSPAN BY MIMICKING THE EFFECTS OF TIME-RESTRICTED FEEDING | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2024-01-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240000753-A1 | METHODS AND COMPOSITIONS TO INCREASE LIFESPAN AND HEALTHSPAN BY MIMICKING THE EFFECTS OF TIME-RESTRICTED FEEDING | ULK1, ULK2, RPS6KA3 | ULK1 1/4885MAPT 583/4885MEN1 3614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.