Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.43 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.43 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.43 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.43 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.43 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.43 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.43 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | CACNA1E | Q15878 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30292526 | 0.88 | GPR119 (0.53) | POLBGPR119RBP4PDE4B | |
| SCHEMBL18765377 | 0.83 | POLB (0.46) | POLBGPR119USP30RORC | |
| SCHEMBL20064508 | 0.82 | HCRTR1 (0.46) | POLBGPR119USP30CACNB4CACNA1A | |
| SCHEMBL15058485 | 0.80 | USP30 (0.49) | GPR119USP30CACNB4CACNA1ACACNA1G | |
| SCHEMBL2995903 | 0.79 | GPR119 (0.51) | POLBGPR119USP30CACNB4CACNA1A | |
| SCHEMBL3001240 | 0.78 | GPR119 (0.52) | POLBGPR119USP30CACNB4CACNA1A | |
| SCHEMBL30599901 | 0.78 | GPR119 (0.52) | POLBGPR119USP30CACNB4CACNA1A | |
| SCHEMBL20064549 | 0.77 | POLB (0.42) | POLBGPR119USP30CACNB4CACNA1A | |
| SCHEMBL30740818 | 0.77 | SCD (0.52) | POLBGPR119CACNB4CACNA1ACACNA1G | |
| SCHEMBL31441685 | 0.77 | POLB (0.46) | POLBGPR119USP30CACNB4CACNA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119487027-A | Compounds as PARP1 inhibitors | 宁波新湾科技发展有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-117545748-A | Benzimidazolyl GLP-1GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods of use thereof | 卡莫特医疗有限公司 | 2024-02-09 | — | — | CN | disclosed |