Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745429 | 0.93 | SMN1; SMN2 (0.42) | SMN1; SMN2APPMAOBALDH1A1LMNA | |
| SCHEMBL30745505 | 0.92 | ABCG2 (0.42) | ACHESMN1; SMN2APPCXCL12MAOB | |
| SCHEMBL30745446 | 0.91 | MAOB (0.44) | SMN1; SMN2APPMEN1KMT2AMAOB | |
| SCHEMBL30745414 | 0.90 | ACHE (0.52) | ACHEBACE1CTSLSMN1; SMN2TUBB4A | |
| SCHEMBL30745455 | 0.88 | ACHE (0.51) | ACHEBACE1CTSLSMN1; SMN2TUBB4A | |
| SCHEMBL30745490 | 0.86 | ACHE (0.54) | ACHEBACE1CTSLSMN1; SMN2TUBB4A | |
| SCHEMBL30745456 | 0.85 | MAPT (0.43) | ACHEBACE1CTSLSMN1; SMN2TUBB4A | |
| SCHEMBL30745442 | 0.82 | ACHE (0.43) | ACHEBACE1SMN1; SMN2APPCXCL12 | |
| SCHEMBL30745467 | 0.81 | ABCG2 (0.46) | ACHEBACE1SMN1; SMN2CXCL12MAOB | |
| SCHEMBL30745493 | 0.81 | ACHE (0.60) | ACHEBACE1CTSLSMN1; SMN2TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567303-A | Chalcone Mannich base compound, pharmaceutical composition, preparation method and application thereof | 安徽中医药大学 | 2024-02-20 | — | — | CN | claimed |
| CN-117567303-A | Chalcone Mannich base compound, pharmaceutical composition, preparation method and application thereof | 安徽中医药大学 | 2024-02-20 | — | — | CN | disclosed |