SCHEMBL3074549

SCHEMBL3074549

C=C1OCCN1C1CCN(C(=O)OC(C)(C)C)CC1O

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.41
USP2 O75604 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
USP30 Q70CQ3 5/20 0.39
GPR119 Q8TDV5 2/20 0.39
HPGD P15428 1/20 0.38
FAAH O00519 1/20 0.38
PIK3CD O00329 1/20 0.36
EPHX1 P07099 1/20 0.36
HPGDS O60760 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3074552 1.00 RECQL (0.41) RECQLUSP2SMN1; SMN2USP30GPR119
SCHEMBL3072326 0.87 RECQL (0.42) RECQLUSP2SMN1; SMN2USP30GPR119
SCHEMBL3075339 0.87 RECQL (0.42) RECQLUSP2SMN1; SMN2USP30GPR119
SCHEMBL3069546 0.76 RECQL (0.43) RECQLUSP2SMN1; SMN2USP30GPR119
SCHEMBL3061497 0.73 RECQL (0.41) RECQLUSP2SMN1; SMN2USP30GPR119
SCHEMBL3061498 0.73 RECQL (0.41) RECQLUSP2SMN1; SMN2USP30GPR119
SCHEMBL24969958 0.73 HPGD (0.51) RECQLUSP2SMN1; SMN2USP30GPR119
SCHEMBL13261499 0.73 HPGD (0.51) RECQLUSP2SMN1; SMN2USP30GPR119
SCHEMBL16661889 0.73 HPGD (0.51) RECQLUSP2SMN1; SMN2USP30GPR119
SCHEMBL1945817 0.73 HPGD (0.51) RECQLUSP2SMN1; SMN2USP30GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100272680-A1 Piperidinyl Cyclic Amido Antiviral Agents BASKARAN SUBRAMANIAN 2010-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100272680-A1 Piperidinyl Cyclic Amido Antiviral Agents ZC3HAV1, MAVS, EIF2AK2 RECQL 1752/4885USP2 3640/4885SMN1; SMN2 2480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.