Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 10/20 | 0.58 |
| ▸ | MEN1 | O00255 | 10/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.58 |
| ▸ | NPC1 | O15118 | 9/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.53 |
| ▸ | RELA | Q04206 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MPI | P34949 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24358218 | 1.00 | GAA (0.63) | GAAALDH1A1TDP1SLC2A1RAB9A | |
| SCHEMBL30745716 | 0.94 | GAA (0.53) | GAAALDH1A1TDP1SLC2A1RAB9A | |
| SCHEMBL24357980 | 0.94 | GAA (0.53) | GAAALDH1A1TDP1SLC2A1RAB9A | |
| SCHEMBL27074002 | 0.87 | TRPV4 (0.47) | GAAALDH1A1TDP1SLC2A1RAB9A | |
| SCHEMBL30745699 | 0.87 | SLC2A1 (0.61) | GAAALDH1A1TDP1SLC2A1RAB9A | |
| SCHEMBL27039731 | 0.87 | SLC2A1 (0.61) | GAAALDH1A1TDP1SLC2A1RAB9A | |
| SCHEMBL24358209 | 0.84 | TRPV4 (0.45) | GAAALDH1A1TDP1SLC2A1RAB9A | |
| SCHEMBL30745677 | 0.84 | TRPV4 (0.45) | GAAALDH1A1TDP1SLC2A1RAB9A | |
| SCHEMBL24357997 | 0.84 | KCNN1 (0.63) | GAAALDH1A1TDP1SLC2A1RAB9A | |
| SCHEMBL30745762 | 0.84 | KCNN1 (0.63) | GAAALDH1A1TDP1SLC2A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025891-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CELGENE CORPORATION | 2024-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240025891-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CYP8B1, PAH, INHA | GAA 1465/4885ALDH1A1 717/4885TDP1 4176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.