Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN1 | Q92952 | 2/20 | 1.00 |
| ▸ | KCNN2 | Q9H2S1 | 2/20 | 1.00 |
| ▸ | KCNN3 | Q9UGI6 | 2/20 | 1.00 |
| ▸ | MECP2 | P51608 | 1/20 | 1.00 |
| ▸ | MBD2 | Q9UBB5 | 1/20 | 1.00 |
| ▸ | NPC1 | O15118 | 11/20 | 0.75 |
| ▸ | RAB9A | P51151 | 9/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.75 |
| ▸ | MEN1 | O00255 | 8/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.74 |
| ▸ | MAPT | P10636 | 6/20 | 0.74 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.74 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.74 |
| ▸ | RELA | Q04206 | 5/20 | 0.74 |
| ▸ | TP53 | P04637 | 4/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.74 |
| ▸ | PPP1CA | P62136 | 2/20 | 0.74 |
| ▸ | ALPL | P05186 | 2/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5155715 | 1.00 | KCNN1 (1.00) | KCNN1KCNN2KCNN3MECP2MBD2 | |
| SCHEMBL7678939 | 0.90 | MAPT (0.81) | KCNN1KCNN2KCNN3MECP2MBD2 | |
| Bromide SCHEMBL7673197 | 0.88 | MAPT (0.79) | KCNN1KCNN2KCNN3MECP2MBD2 | |
| SCHEMBL27800934 | 0.87 | MECP2 (0.77) | KCNN1KCNN2KCNN3MECP2MBD2 | |
| SCHEMBL7552748 | 0.87 | NPC1 (0.91) | KCNN1KCNN2KCNN3MECP2MBD2 | |
| SCHEMBL15993486 | 0.87 | KCNN1 (0.76) | KCNN1KCNN2KCNN3MECP2MBD2 | |
| SCHEMBL15993207 | 0.87 | KCNN1 (0.76) | KCNN1KCNN2KCNN3MECP2MBD2 | |
| Bromide SCHEMBL7669000 | 0.86 | NPC1 (0.88) | KCNN1KCNN2KCNN3MECP2MBD2 | |
| SCHEMBL16217145 | 0.86 | NPC1 (1.00) | KCNN1KCNN2KCNN3MECP2MBD2 | |
| SCHEMBL4397255 | 0.86 | KMT2A (1.00) | KCNN1KCNN2KCNN3MECP2MBD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025891-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CELGENE CORPORATION | 2024-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240025891-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CYP8B1, PAH, INHA | KCNN1 4605/4885KCNN2 4592/4885KCNN3 4470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.