Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.81 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.81 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.81 |
| ▸ | RELA | Q04206 | 3/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.81 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.81 |
| ▸ | MEN1 | O00255 | 3/20 | 0.81 |
| ▸ | PPP1CA | P62136 | 2/20 | 0.81 |
| ▸ | KCNN1 | Q92952 | 2/20 | 0.81 |
| ▸ | KCNN2 | Q9H2S1 | 2/20 | 0.81 |
| ▸ | MBD2 | Q9UBB5 | 2/20 | 0.81 |
| ▸ | KCNN3 | Q9UGI6 | 2/20 | 0.81 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.81 |
| ▸ | MECP2 | P51608 | 1/20 | 0.81 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.72 |
| ▸ | VCP | P55072 | 1/20 | 0.72 |
| ▸ | SLC2A1 | P11166 | 5/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7673197 | 0.98 | MAPT (0.79) | MAPTKMT2ANFKB1NFKB2RELA | |
| SCHEMBL29602125 | 0.91 | MAPT (0.74) | MAPTKMT2ANFKB1NFKB2RELA | |
| SCHEMBL6368825 | 0.91 | MAPT (0.74) | MAPTKMT2ANFKB1NFKB2RELA | |
| SCHEMBL6368488 | 0.91 | MAPT (0.68) | MAPTKMT2ANFKB1NFKB2RELA | |
| SCHEMBL30745771 | 0.90 | KCNN1 (1.00) | MAPTKMT2ANFKB1NFKB2RELA | |
| SCHEMBL5155715 | 0.90 | KCNN1 (1.00) | MAPTKMT2ANFKB1NFKB2RELA | |
| SCHEMBL12639826 | 0.90 | SMN1; SMN2 (1.00) | MAPTKMT2ANFKB1NFKB2RELA | |
| SCHEMBL3401851 | 0.85 | NPC1 (0.73) | MAPTKMT2ANFKB1NFKB2RELA | |
| SCHEMBL1887374 | 0.85 | VCP (1.00) | MAPTKMT2ANFKB1NFKB2RELA | |
| SCHEMBL13803792 | 0.85 | MAPT (0.78) | MAPTKMT2ANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6391894-B1 | ANTICANCER AGENTS; ANTIPROLIFERATIVE AGENTS | SMITHKLINE BEECHAM CORPORATION | 2002-05-21 | — | — | US | claimed |