SCHEMBL30745904

SCHEMBL30745904

NC(=O)c1ccc(OCc2ccc(SC(F)(F)F)cc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTPRZ1 P23471 1/20 0.72
PARP10 Q53GL7 9/20 0.69
MAOB P27338 7/20 0.68
PARP15 Q460N3 2/20 0.49
PARP14 Q460N5 2/20 0.49
F2 P00734 2/20 0.49
PRSS1 P07477 1/20 0.49
PRSS2 P07478 1/20 0.49
PRSS3 P35030 1/20 0.49
TMPRSS6 Q8IU80 1/20 0.49
ST14 Q9Y5Y6 1/20 0.49
PTPN2 P17706 2/20 0.48
PTPN1 P18031 2/20 0.48
PTPN7 P35236 1/20 0.48
NR4A2 P43354 1/20 0.48
PTPRC P08575 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3275286 0.86 PTPRZ1 (0.72) PTPRZ1MAOBPTPN2PTPN1PTPN7
Lithium Ion SCHEMBL3275290 0.85 PTPRZ1 (0.70) PTPRZ1PARP10MAOBPTPN2PTPN1
SCHEMBL3275342 0.84 PTPRZ1 (0.68) PTPRZ1MAOBPTPN2PTPN1PTPN7
SCHEMBL30885390 0.83 PTPRZ1 (0.67) PTPRZ1PARP10MAOBPTPN2PTPN1
SCHEMBL2541283 0.82 KIF11 (0.54) PTPRZ1PARP10PARP15PARP14PTPN1
SCHEMBL22721364 0.81 PARP10 (0.76) PARP10MAOBPARP15PARP14F2
SCHEMBL30576796 0.81 MAOB (1.00) PARP10MAOBNR4A2
SCHEMBL29279866 0.81 PTPRZ1 (0.63) PTPRZ1PARP10MAOBPTPN2PTPN1
SCHEMBL1378500 0.80 FGFR1 (0.53) PTPRZ1PARP10MAOBPTPN2PTPN1
SCHEMBL30745888 0.78 EPHX2 (0.46) PTPRZ1MAOBPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117682973-A Sulfonamide compound and medical application thereof 中国药科大学 2024-03-12 CN disclosed