SCHEMBL3074596

SCHEMBL3074596

C/C=N\Nc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 2/20 0.58
MAPT P10636 8/20 0.48
GAA P10253 6/20 0.48
MEN1 O00255 6/20 0.48
KMT2A Q03164 6/20 0.48
ALDH1A1 P00352 6/20 0.48
HPGD P15428 3/20 0.48
RAB9A P51151 3/20 0.48
LMNA P02545 2/20 0.48
GFER P55789 2/20 0.48
TDP1 Q9NUW8 4/20 0.43
SMN1; SMN2 Q16637 4/20 0.43
KDM4E B2RXH2 2/20 0.43
MAPK1 P28482 1/20 0.43
TSHR P16473 2/20 0.43
CYP1A1 P04798 1/20 0.43
CYP1B1 Q16678 1/20 0.43
SENP7 Q9BQF6 2/20 0.42
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1005100 1.00 NOX1 (0.58) NOX1MAPTGAAMEN1KMT2A
SCHEMBL3074599 1.00 NOX1 (0.58) NOX1MAPTGAAMEN1KMT2A
SCHEMBL11831353 0.98 NOX1 (0.56) NOX1MAPTGAAMEN1KMT2A
SCHEMBL11831344 0.98 NOX1 (0.56) NOX1MAPTGAAMEN1KMT2A
SCHEMBL16111932 0.79 NOX1 (0.62) NOX1MAPTGAAMEN1KMT2A
SCHEMBL16111930 0.79 NOX1 (0.62) NOX1MAPTGAAMEN1KMT2A
SCHEMBL13109406 0.79 NOX1 (0.62) NOX1MAPTGAAMEN1KMT2A
SCHEMBL765856 0.78 GAA (0.52) MAPTGAAMEN1KMT2AALDH1A1
SCHEMBL14438098 0.76 MAPT (0.50) MAPTGAAMEN1KMT2AALDH1A1
SCHEMBL1002645 0.76 NOX1 (0.34) NOX1MAPTGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4410457-A EPOXY REACTIVE SOLVENT, EPOXY RESIN, LATENT HARDENER, EPOXIDE-DIALKYLAMINE ADDUCT SUMITOMO CHEMICAL CO., LTD. (JP) 1983-10-18 US claimed
US-20260009142-A1 Electrochemical synthesis of pyrazolines and pyrazoles BAYER AG (DE) 2026-01-08 US disclosed
EP-4555128-A1 ELECTROCHEMICAL SYNTHESIS OF PYRAZOLINES AND PYRAZOLES Bayer Aktiengesellschaft (DE) 2025-05-21 EP disclosed
CN-119698496-A Electrochemical synthesis of pyrazolines and pyrazoles 拜耳公司 2025-03-25 CN disclosed
WO-2025003282-A2 ATP PRODUCTION FROM ELECTRICITY WITH A NEW-TO-NATURE ELECTROBIOLOGICAL MODULE MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2025-01-02 WO disclosed
EP-4484566-A1 ATP PRODUCTION FROM ELECTRICITY WITH A NEW-TO-NATURE ELECTROBIOLOGICAL MODULE Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2025-01-01 EP disclosed
WO-2024012791-A1 ELECTROCHEMICAL SYNTHESIS OF PYRAZOLINES AND PYRAZOLES BAYER AKTIENGESELLSCHAFT (DE) 2024-01-18 WO disclosed
US-11851391-B2 Antifungal compounds and methods of forming the same UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2023-12-26 US disclosed
EP-3828179-A1 CYANOPYRROLIDINES AS DUB MODULATORS Mission Therapeutics Limited (GB) 2021-06-02 EP disclosed
US-20200024224-A1 ANTIFUNGAL COMPOUNDS AND METHODS OF FORMING THE SAME UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2020-01-23 US disclosed
CN-1041084-A Edible fungus inoculation method LI YUNLONG (CN) 1990-04-11 CN disclosed
EP-0274114-A2 Heat curable organopolysiloxane compositions Wacker Silicones Corporation (US) 1988-07-13 EP disclosed
US-4725628-A Process of making a crosslinked superabsorbent polyurethane foam KIMBERLY-CLARK CORPORATION (US) 1988-02-16 US disclosed
US-4710559-A Heat curable organopolysiloxane compositions WACKER SILICONES CORPORATION (US) 1987-12-01 US disclosed
EP-0039230-B1 CURABLE COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-12-11 EP disclosed
US-4410457-A EPOXY REACTIVE SOLVENT, EPOXY RESIN, LATENT HARDENER, EPOXIDE-DIALKYLAMINE ADDUCT SUMITOMO CHEMICAL CO., LTD. (JP) 1983-10-18 US disclosed
US-4360649-A EPOXY RESIN, EPOXIDE-DIALKYLAMINE ADDUCT, UREA COMPOUND, CURING AGENTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-11-23 US disclosed
EP-0039230-A2 Curable composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-11-04 EP disclosed
US-4172835-A URINARY ANTISEPTIC, HYPOTENSIVE AGENT AND HYPOGLYCEMIC AGENT STERLING DRUG INC. (US) 1979-10-30 US disclosed
US-3948939-A 9-Acyl-1,2,3,4-tetrahydrocarbazole-3 and 4-carboxylic acids STERLING DRUG INC. (US) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260009142-A1 Electrochemical synthesis of pyrazolines and pyrazoles CYP2E1, CYP2F1, CYP4F2 NOX1 280/4885MAPT 4836/4885GAA 3100/4885
US-11851391-B2 Antifungal compounds and methods of forming the same DPM1, ERG28, SUCLG1 NOX1 151/4885MAPT 1403/4885GAA 202/4885
US-20200024224-A1 ANTIFUNGAL COMPOUNDS AND METHODS OF FORMING THE SAME DPM1, ERG28, SUCLG1 NOX1 151/4885MAPT 1403/4885GAA 202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.