Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 8/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.51 |
| ▸ | NTMT1 | Q9BV86 | 2/20 | 0.50 |
| ▸ | UGCG | Q16739 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16007049 | 1.00 | CHRM3 (0.51) | CHRM3CHRM2CHRM1NTMT1UGCG | |
| SCHEMBL16007046 | 1.00 | CHRM3 (0.51) | CHRM3CHRM2CHRM1NTMT1UGCG | |
| SCHEMBL16007093 | 0.92 | CHRM3 (0.42) | CHRM3CHRM2CHRM1NTMT1UGCG | |
| SCHEMBL29415407 | 0.90 | CHRM2 (0.51) | CHRM3CHRM2CHRM1NTMT1UGCG | |
| SCHEMBL16007179 | 0.90 | CHRNA7 (0.59) | CHRM3CHRM2CHRM1CHRNA7BCHE | |
| SCHEMBL31613798 | 0.89 | CHRM3 (0.52) | CHRM3CHRM2CHRM1NTMT1UGCG | |
| SCHEMBL29356569 | 0.89 | CHRM3 (0.55) | CHRM3CHRM2CHRM1NTMT1UGCG | |
| SCHEMBL16007010 | 0.88 | CHRM2 (0.45) | CHRM3CHRM2CHRM1NTMT1UGCG | |
| SCHEMBL16007009 | 0.88 | CHRM2 (0.45) | CHRM3CHRM2CHRM1NTMT1UGCG | |
| SCHEMBL29356578 | 0.87 | NTMT1 (0.52) | CHRM3CHRM2CHRM1NTMT1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3267983-B1 | METHODS FOR TREATING PROTEINOPATHIES | GENZYME CORP (US) | 2023-12-20 | — | — | EP | disclosed |