Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.46 |
| ▸ | ATXN2 | Q99700 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27194542 | 0.88 | MEN1 (0.47) | ENPP2ATXN2MEN1KMT2ANPSR1 | |
| SCHEMBL9572627 | 0.84 | MEN1 (0.57) | MEN1KMT2ANPSR1NPC1RAB9A | |
| SCHEMBL30746332 | 0.82 | MEN1 (0.51) | ENPP2ATXN2MEN1KMT2ANPSR1 | |
| SCHEMBL2845596 | 0.81 | MEN1 (0.51) | ENPP2ATXN2MEN1KMT2ANPSR1 | |
| SCHEMBL5406165 | 0.79 | TMEM97 (0.52) | MEN1KMT2ANPSR1NPC1RAB9A | |
| SCHEMBL5406156 | 0.79 | TMEM97 (0.52) | MEN1KMT2ANPSR1NPC1RAB9A | |
| SCHEMBL25376016 | 0.79 | ENPP2 (0.55) | ENPP2ATXN2MEN1KMT2ANPSR1 | |
| SCHEMBL30720175 | 0.78 | MEN1 (0.45) | ENPP2ATXN2MEN1KMT2ANPSR1 | |
| SCHEMBL7711512 | 0.77 | ENPP2 (0.54) | ENPP2ATXN2MEN1KMT2ANPSR1 | |
| SCHEMBL14731552 | 0.77 | ENPP2 (0.59) | ENPP2ATXN2MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4554948-A1 | TETRAHYDRONAPHTHALENE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS | Regents of the University of Michigan (US) | 2025-05-21 | — | — | EP | disclosed |